崔红梅
基本情况
崔红梅，教授，卫生毒理学研究所，博士，硕士研究生导师（专业型和学术型）。
学习经历
1993.9—2000.07 宁夏医科大学公共卫生学院预防医学，学士
2000.9—2003.07 东南大学公共卫生学院劳动卫生与环境卫生学，硕士
2008.09-2009.09 美国Texas A&M University, 毒理系，联合培养博士
2006.9—2010.07 复旦大学公共卫生学院劳动卫生与毒理学，博士
工作经历
2003.07— 2006.05 南京医科大学公共卫生学院，助理研究员
2011.01— 2011.09 江苏省疾病预防控制中心，公卫医师
2011.10— 2013.07 美国Albany Medical College,细胞生物系，博士后
2013.08— 2015.10 美国Georgia Cancer Center,博士后
2015.11— 2017.11 美国St. Jude Children’s Research Center,生物治疗系，博士后
2018.03— 2019.03 美国 University of Tennessee, 药理系，博士后
2019.04— 至今 兰州大学公共卫生学院，教授
目前承担课程
预防医学》、《卫生毒理学》等，其中《预防医学》为甘肃省精品课程。
主要科研成果
研究方向：
1. 蛋白质泛素化修饰在DNA损伤修复中的作用研究
2. 肿瘤的耐药机制研究
发表主要论文或专著:
[1] Niu X, Wu T, Li G, Gu X, Tian Y*, Cui H*. Insights into the critical role of the PXR in preventing carcinogenesis and chemotherapeutic drug resistance. Int J Biol Sci. 2022 Jan 1;18(2):742-759. doi: 10.7150/ijbs.68724. eCollection 2022. (Q1, 2022 Real-time IF:11.6)
[2] Wu T, Gu X, Cui H*. Emerging Roles of SKP2 in Cancer Drug Resistance. Cells. 2021 May 10;10(5):1147. doi: 10.3390/cells10051147. (Q2, IF:7.5)
[3] Niu X, Cui H*, Gu X*, Wu T, Sun M, Zhou C, Ma M. Nuclear receptor PXR confers irradiation resistance by promoting DNA damage response through stabilization of ATF3. Front Oncol. 2022 Mar 16;12:837980. doi: 10.3389/fonc.2022.837980. eCollection 2022. (Q2, IF:6.2)
[4] Wu T, Li C, Zhou C, Niu X, Li G, Zhou Y, GuX*, Cui H*.Inhibition of USP14 enhances anti-tumor effect in vemurafenib-resistant melanoma by regulation of Skp2. Cell Biology and Toxicology. (Accept) (Q1, IF:6.7)
[5] Cui H, Arnst K, Miller DD, Li W*. Recent advances on elucidating paclitaxel resistance mechanisms in non-small cell lung cancer and strategies to overcome drug resistance. Current Medicinal Chemistry. 2019. DOI: 10.2174/0929867326666191016113631 (IF=4.184, Q1)
[6] Cui H, Gu X, Chen J, Xie Y, Ke Sui, Wu J, Golovko A, Morpurgo B, Yan C, Phillips TD, Xie W, Luo J, Zhou Z, Tian Y*. Preganane X receptor regulates the AhR/CYP1A1 pathway and protects liver cells from Benzo-[a]-Pyrene-incuced DNA damage. Toxicology Letters. 2017 Jun 5; 275:67-76. (IF=3.569, Q1)
[7] Peter O#, Cui H#, Zhang C#, Chen T*. Regulation of PXR and CAR by protein-protein interaction and signaling crosstalk. Expert Opin Drug Metab Toxicol. 2016 Jun 23:1-14. (IF=3.47, Q1)(citation：11)
[8] Cui H, Li X, Han C, Wang QE, Wang H, Ding HF, Zhang J, Yan C*. The Stress-responsive Gene ATF3 Mediates Dichotomous UV Responses by Regulating the Tip60 and p53 Proteins. J Biol Chem. 2016, 291(20):10847-57. (IF=4.238, Q1)
[10] Cui HM, Guo M, Xu D, Ding ZC, Zhou G, Ding HF, Zhang J, Tang Y, Yan C*. The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60. Nat Commun. 2015, 6:6752. (IF=12.121, Q1) (citation:19)
社会兼职和社会服务
1.《环境与职业医学》海外编委
2. 美国肿瘤协会会员
3. 美国毒理学会会员
办公电话
0391-8911745