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                            <h2>马彦荣</h2>
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                <p style="text-indent: 32px; line-height: 150%; text-align: center;"><strong><span style="font-family: &#39;Times New Roman&#39;;line-height: 150%;font-size: 16px"><span style="font-family:黑体"><img src="../../hdupf/img/202304/202304121681285341618524.jpg"/></span></span></strong></p><p style="text-indent:32px;line-height:150%"><strong><span style="font-family: &#39;Times New Roman&#39;;line-height: 150%;font-size: 16px"><span style="font-family:黑体">【基本情况】</span></span></strong></p><p style="text-indent:32px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px"><span style="font-family:Tahoma 宋体">马彦荣，主管药师，</span></span><span style=";font-family:&#39;Tahoma 宋体&#39;;line-height:150%;font-size:16px">第一临床医学院</span><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px"><span style="font-family:Tahoma 宋体">，学术型硕士研究生导师。</span></span></p><p style="text-indent:32px;line-height:150%"><strong><span style="font-family: &#39;Times New Roman&#39;;line-height: 150%;font-size: 16px"><span style="font-family:黑体">【学习经历】</span></span></strong></p><p style="text-indent:32px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">2008.9—2012.07 &nbsp;<span style="font-family:宋体">兰州大学药学院，学士</span></span></p><p style="text-indent:32px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">2012.9—2015.07 &nbsp;<span style="font-family:宋体">兰州大学药学院，硕士</span></span></p><p style="text-indent:32px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">2018.9—2022.07 &nbsp;<span style="font-family:宋体">兰州大学药学院，博士</span></span></p><p style="text-indent:32px;line-height:150%"><strong><span style="font-family: &#39;Times New Roman&#39;;line-height: 150%;font-size: 16px"><span style="font-family:Tahoma 宋体">【工作经历】</span></span></strong></p><p style="text-indent:32px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">2015.07— 2020.07 &nbsp;<span style="font-family:宋体">兰州大学第一临床医学院，药师</span></span></p><p style="text-indent:32px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">2020.08— <span style="font-family:宋体">至今 &nbsp;&nbsp;兰州大学第一临床医学院，主管药师</span></span></p><p style="text-indent:32px;line-height:150%"><strong><span style="font-family: &#39;Times New Roman&#39;;line-height: 150%;font-size: 16px"><span style="font-family:Tahoma 宋体">【目前承担课程】</span></span></strong></p><p style="text-indent:32px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;color:rgb(51,51,51);font-size:16px;background:rgb(255,255,255)"><span style="font-family:宋体">《药物转运体研究进展》</span></span></p><p style="text-indent:32px;line-height:150%"><strong><span style="font-family: &#39;Times New Roman&#39;;line-height: 150%;font-size: 16px"><span style="font-family:Tahoma 宋体">【主要科研成果】</span></span></strong></p><p style="text-indent:48px;line-height:150%"><strong><span style="font-family: &#39;Times New Roman&#39;;line-height: 150%;font-size: 16px"><span style="font-family:Tahoma 宋体">研究方向：</span></span></strong><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px"><span style="font-family:Tahoma 宋体">基于转运体的肾脏排泄功能评价及药物毒性研究。</span></span></p><p style="text-indent:48px;line-height:150%"><strong><span style="font-family: &#39;Times New Roman&#39;;line-height: 150%;font-size: 16px"><span style="font-family:Tahoma 宋体">主持或参与科研项目：</span></span></strong></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">1. <span style="font-family:宋体">国家自然科学基金地区项目，</span><span style="font-family:Times New Roman">82160705</span><span style="font-family:宋体">，肌酐通过</span><span style="font-family:Times New Roman">cGMP-PKG</span><span style="font-family:宋体">促进肾小管</span><span style="font-family:Times New Roman">OATs-MRPs</span><span style="font-family:宋体">通道分泌功能的机制研究，</span><span style="font-family:Times New Roman">2022.01-2025.12</span><span style="font-family:宋体">，</span><span style="font-family:Times New Roman">34</span><span style="font-family:宋体">万元，在研，主持</span></span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">2. <span style="font-family:宋体">国家自然科学基金青年项目，</span><span style="font-family:Times New Roman">81803611</span><span style="font-family:宋体">，从蛋白结合型尿毒素中筛选肾小管</span><span style="font-family:Times New Roman">OATs-MRPs</span><span style="font-family:宋体">通道功能评价的特异性标志物，</span><span style="font-family:Times New Roman">2019/01-2021/12</span><span style="font-family:宋体">，</span><span style="font-family:Times New Roman">21.5</span><span style="font-family:宋体">万元，结题，主持</span></span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">3. <span style="font-family:宋体">甘肃省重大专项，</span><span style="font-family:Times New Roman">21ZD4FA014</span><span style="font-family:宋体">，基于肾小管分泌和重吸收转运体的早期肾损伤内源性标志物筛选及初步产业化，</span><span style="font-family:Times New Roman">2021.10-2024.9</span><span style="font-family:宋体">，</span><span style="font-family:Times New Roman">300</span><span style="font-family:宋体">万元，在研，子课题负责人</span></span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">4. <span style="font-family:宋体">国家自然科学基金联合基金重点支持项目，</span><span style="font-family:Times New Roman">U21A20424</span><span style="font-family:宋体">，基于转运体筛选评价肾小管分泌和重吸收功能的内源性标志物并构建准确预测药物肾排泄能力的</span><span style="font-family:Times New Roman">PBPK</span><span style="font-family:宋体">模型，</span><span style="font-family:Times New Roman">2022/01-2025/12</span><span style="font-family:宋体">，</span><span style="font-family:Times New Roman">270</span><span style="font-family:宋体">万元，在研，参加（</span><span style="font-family:Times New Roman">2/10</span><span style="font-family:宋体">）</span></span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">5. <span style="font-family:宋体">中华医学会吴阶平医学基金会临床科研专项，</span><span style="font-family:Times New Roman">320.6750.2020-04-41</span><span style="font-family:宋体">，基于</span><span style="font-family:Times New Roman">cGMP-PKG-OAT2</span><span style="font-family:宋体">通路研究慢性肾损伤后肌酐肾小管转运增加的机制，</span><span style="font-family:Times New Roman">2020/01-2021/12</span><span style="font-family:宋体">，</span><span style="font-family:Times New Roman">5</span><span style="font-family:宋体">万元，结题，主持</span></span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">6. <span style="font-family:宋体">甘肃省自然科学基金青年基金项目，</span><span style="font-family:Times New Roman">20JR10RA708</span><span style="font-family:宋体">，基于血清离体肾灌流</span><span style="font-family:Times New Roman">-</span><span style="font-family:宋体">尿液代谢组学从尿毒素</span><span style="font-family:Times New Roman">(</span><span style="font-family:宋体">群</span><span style="font-family:Times New Roman">)</span><span style="font-family:宋体">中筛选特异性肾小球滤过的内源性标志物，</span><span style="font-family:Times New Roman">2021/02-2023/02, 2</span><span style="font-family:宋体">万元，结题，主持</span></span></p><p style="text-indent:48px;line-height:150%"><strong><span style="font-family: &#39;Times New Roman&#39;;line-height: 150%;font-size: 16px"><span style="font-family:Tahoma 宋体">发表主要论文或专著</span>:</span></strong><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">&nbsp;</span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">1. Yanrong Ma, Mingkang Zhang, Jinru Yang, Lin Zhu, Jianye Dai, Xinan Wu</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">*</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, Characterization of the renal tubular transport of creatinine by activity-based protein profiling and transport kinetics, European Journal of Pharmaceutical Sciences 2023 (180):106342</span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">2. Xueyan Gou, Fenglin Ran, Jinru Yang, Yanrong Ma</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">*</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, Xin’an Wu</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">*</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, Construction and evaluation of a novel organic anion transporter 1/3 CRISPR/Cas9 double-knockout rat model, Pharmaceutics, 2022, 14: 2307</span><span style=";font-family:&#39;Tahoma 宋体&#39;;line-height:150%;font-size:16px">（共同通讯）</span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">3. Yanrong Ma, Mingyan Xin, Yuanjie Wen, Huan Wang, Guoqiang Zhang, Jianye Dai*, Xin-An Wu*, The utility of endogenous glycochenodeoxycholate-3-sulfate and 4β-hydroxycholesterol to evaluate the hepatic disposition of atorvastatin in rats, Asian Journal of Pharmaceutical Sciences, 2021, 16(4): 519-529.</span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">4. Yanrong Ma</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">#</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, Ming-yan Xin</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">#</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, Kan Li</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">#</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, Huan Wang, Zhi Rao, Tian-xi Liu</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">*</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, Xin-an Wu</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">*</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, An LC-MS/MS analytical method for the determination of uremic toxins in patients with end-stage renal disease, Journal of Pharmaceutical and Biomedical Analysis, 2020, 191, 113551.</span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">5. Yanrong Ma</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">#</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, Yan Zhou</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">#</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, Jing Huang, Hongyan Qin, Pei Wang, Xinan Wu, The urinary excretion of metformin, ceftizoxime and ofloxacin in high serum creatinine rats: Can creatinine predict renal tubular elimination? Life Sciences, 2018, 196: 110-117.</span></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">6. Yanrong Ma, Xuan Luo, Yanfang Wu, Tiffany Zhang, Fan Zhang, Guoqiang Zhang, Xinan Wu</span><sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px;vertical-align:super">*</span></sup><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">, Alteration of renal excretion pathways in gentamicin-induced renal injury in rats, Journal of Applied Toxicology, 2018, 38: 968-977.</span></p><p style="text-indent:32px;line-height:150%"><strong><span style="font-family: &#39;Times New Roman&#39;;line-height: 150%;font-size: 16px"><span style="font-family:Tahoma 宋体">【联系方式】</span></span></strong></p><p style="text-indent:48px;line-height:150%"><span style=";font-family:&#39;Times New Roman&#39;;line-height:150%;font-size:16px">E-mail<span style="font-family:Tahoma 宋体">：</span><span style="font-family:Times New Roman">ldyy_mayrong@lzu.edu.cn</span></span></p><p><br/></p>            </div>
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